Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | BIOCARTA_ROLE OF MAL IN RHO-MEDIATED ACTIVATION OF SRF |
| Enrichment Score (ES) | -0.75662553 |
| Normalized Enrichment Score (NES) | -1.6852249 |
| Nominal p-value | 0.0076045627 |
| FDR q-value | 0.14959337 |
| FWER p-Value | 0.868 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MAP2K2 | 1415974_at 1443436_at 1460636_at | 6734 | 0.192 | -0.2882 | No | ||
| 2 | RAC1 | 1423734_at 1437674_at 1451086_s_at | 6772 | 0.190 | -0.2710 | No | ||
| 3 | HRAS | 1422407_s_at 1424132_at | 7807 | 0.155 | -0.3028 | No | ||
| 4 | SRF | 1418255_s_at 1418256_at | 9000 | 0.117 | -0.3456 | No | ||
| 5 | LIMK1 | 1417627_a_at 1425836_a_at 1456234_at 1458989_at | 10271 | 0.080 | -0.3956 | No | ||
| 6 | MAL | 1417275_at 1432558_a_at | 11202 | 0.054 | -0.4327 | No | ||
| 7 | MAP2K1 | 1416351_at | 16004 | -0.128 | -0.6391 | No | ||
| 8 | ROCK1 | 1423444_at 1423445_at 1441162_at 1446518_at 1450994_at 1460729_at | 16107 | -0.135 | -0.6303 | No | ||
| 9 | MAPK8 | 1420931_at 1420932_at 1437045_at 1440856_at 1457936_at | 16138 | -0.137 | -0.6182 | No | ||
| 10 | RHOA | 1437628_s_at | 16372 | -0.153 | -0.6136 | No | ||
| 11 | ACTA1 | 1427735_a_at | 19508 | -0.620 | -0.6952 | Yes | ||
| 12 | MAPK3 | 1427060_at | 19557 | -0.635 | -0.6345 | Yes | ||
| 13 | MAP4K2 | 1428297_at 1434833_at 1450244_a_at | 19638 | -0.659 | -0.5729 | Yes | ||
| 14 | RAF1 | 1416078_s_at 1425419_a_at | 20130 | -0.828 | -0.5132 | Yes | ||
| 15 | MAP3K1 | 1424850_at | 21056 | -1.420 | -0.4147 | Yes | ||
| 16 | MAPK1 | 1419568_at 1426585_s_at 1442876_at 1453104_at | 21390 | -1.864 | -0.2453 | Yes | ||
| 17 | CDC42 | 1415724_a_at 1435807_at 1449574_a_at 1460708_s_at | 21696 | -2.726 | 0.0109 | Yes |
